• Bullerwell, C. E., Robichaud, P. P., Deprez, P. M. L., Joy, A. P., Wajnberg, G., D’Souza, D., Chacko, S., Fournier, S., Crapoulet, N., Barnett, D. A., Lewis, S. M., & Ouellette, R. J. (2021). EBF1 drives hallmark B cell gene expression by enabling the interaction of PAX5 with the MLL H3K4 methyltransferase complex.Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-81000-5
  • Kumar, A., Dhadi, S. R., Mai, N., Taylor, C., Roy, J. W., Barnett, D. A., Lewis, S. M., Ghosh, A., & Ouellette, R. J. (2021). The polysaccharide chitosan facilitates the isolation of small extracellular vesicles from multiple biofluids. Journal of Extracellular Vesicles, 10(11). https://doi.org/10.1002/jev2.12138
  • Murphy, E. L., Joy, A. P., Ouellette, R. J., & Barnett, D. A. (2021). Optimization of cysteine residue alkylation using an on-line LC-MS strategy: Benefits of using a cocktail of haloacetamide reagents.Analytical Biochemistry, 619, 114137. https://doi.org/10.1016/j.ab.2021.114137
  • Roy, J. W., Taylor, C. A., Beauregard, A. P., Dhadi, S. R., Ayre, D. C., Fry, S., Chacko, S., Wajnberg, G., Joy, A. P., Mai-Thi, N. N., Crapoulet, N., Barnett, D. A., Ghosh, A., Lewis, S. M., & Ouellette, R. J. (2021). A multiparametric extraction method for Vn96-isolated plasma extracellular vesicles and cell-free DNA that enables multi-omic profiling.Scientific Reports, 11(1). https://doi.org/10.1038/s41598-021-87526-y
  • Bastarache, P., Wajnberg, G., Dumas, P., Chacko, S., Lacroix, J., Crapoulet, N., Moffat, C. E., & Morin, P. (2020). Transcriptomics-Based Approach Identifies Spinosad-Associated Targets in the Colorado Potato Beetle, Leptinotarsa decemlineata. Insects11(11), 820. https://doi.org/10.3390/insects11110820
  • Bera, A., & Lewis, S. M. (2020). Regulation of Epithelial-to-Mesenchymal Transition by Alternative Translation Initiation Mechanisms and Its Implications for Cancer Metastasis.International Journal of Molecular Sciences, 21(11), 4075. https://doi.org/10.3390/ijms21114075
  • Davey, M., Benzina, S., Savoie, M., Breault, G., Ghosh, A., & Ouellette, R. J. (2020). Affinity Captured Urinary Extracellular Vesicles Provide mRNA and miRNA Biomarkers for Improved Accuracy of Prostate Cancer Detection: A Pilot Study.International Journal of Molecular Sciences, 21(21), 8330. https://doi.org/10.3390/ijms21218330
  • Murphy, E. L., Joy, A. P., Ouellette, R. J., & Barnett, D. A. (2020). Improved intact peptide and protein quantitation by LC‐MS: Battling the deleterious effects of analyte adsorption.Analytical Science Advances, 2(5–6), 299–307. https://doi.org/10.1002/ansa.202000102
  • Rangel-Pozzo, A., Liu, S., Wajnberg, G., Wang, X., Ouellette, R. J., Hicks, G. G., Drachenberg, D., & Mai, S. (2020). Genomic Analysis of Localized High-Risk Prostate Cancer Circulating Tumor Cells at the Single-Cell Level. Cells9(8), 1863. https://doi.org/10.3390/cells9081863
  • Smith, N. C., Wajnberg, G., Chacko, S., Woldemariam, N. T., Lacroix, J., Crapoulet, N., Ayre, D. C., Lewis, S. M., Rise, M. L., Andreassen, R., & Christian, S. L. (2020). Characterization of miRNAs in Extracellular Vesicles Released From Atlantic Salmon Monocyte-Like and Macrophage-Like Cells. Frontiers in Immunology11
    https://doi.org/10.3389/fimmu.2020.587931
  • Taylor, C., Chacko, S., Davey, M., Lacroix, J., MacPherson, A., Finn, N., Wajnberg, G., Ghosh, A., Crapoulet, N., Lewis, S. M., & Ouellette, R. J. (2020). Peptide-Affinity Precipitation of Extracellular Vesicles and Cell-Free DNA Improves Sequencing Performance for the Detection of Pathogenic Mutations in Lung Cancer Patient Plasma.International Journal of Molecular Sciences, 21(23), 9083. https://doi.org/10.3390/ijms21239083
  • Wall, M. L., Bera, A., Wong, F. K., & Lewis, S. M. (2020). Cellular stress orchestrates the localization of hnRNP H to stress granules. Experimental Cell Research, 394(1), 112111. https://doi.org/10.1016/j.yexcr.2020.112111
  • Blunck, C. B., Terra-Granado, E., Noronha, E. P., Wajnberg, G., Passetti, F., Pombo-de-Oliveira, M. S., & Emerenciano, M. (2019). CD9 predicts ETV6-RUNX1 in childhood B-cell precursor acute lymphoblastic leukemia. Hematology, Transfusion and Cell Therapy, 41(3), 205–211. https://doi.org/10.1016/j.htct.2018.11.007
  • Bouhamdani, N., Comeau, D., Coholan, A., Cormier, K., & Turcotte, S. (2019). Targeting lysosome function causes selective cytotoxicity in VHL-inactivated renal cell carcinomas.Carcinogenesis, 41(6), 828–840. https://doi.org/10.1093/carcin/bgz161
  • Baig, M. H., Adil, M., Khan, R., Dhadi, S., Ahmad, K., Rabbani, G., Bashir, T., Imran, M. A., Husain, F. M., Lee, E. J., Kamal, M. A., & Choi, I. (2019). Enzyme targeting strategies for prevention and treatment of cancer: Implications for cancer therapy. Seminars in Cancer Biology, 56, 1–11. https://doi.org/10.1016/j.semcancer.2017.12.003

  • Grieve, S., Wajnberg, G., Lees, M., Chacko, S., Weir, J., Crapoulet, N., & Reiman, T. (2019). TAZ functions as a tumor suppressor in multiple myeloma by downregulating MYC.Blood Advances, 3(22), 3613–3625. https://doi.org/10.1182/bloodadvances.2019000374
  • Bouhamdani, N., Comeau, D., Cormier, K., & Turcotte, S. (2019). STF-62247 accumulates in lysosomes and blocks late stages of autophagy to selectively target von Hippel-Lindau-inactivated cells.American Journal of Physiology-Cell Physiology, 316(5), C605–C620. https://doi.org/10.1152/ajpcell.00483.2018
  • Harquail, J., LeBlanc, N., Ouellette, R. J., & Robichaud, G. A. (2019). miRNAs 484 and 210 regulate Pax-5 expression and function in breast cancer cells.Carcinogenesis, 40(8), 1010–1020. https://doi.org/10.1093/carcin/bgy191
  • Mbarik, M., Poirier, S. J., Doiron, J., Selka, A., Barnett, D. A., Cormier, M., Touaibia, M., & Surette, M. E. (2019). Phenolic acid phenethylesters and their corresponding ketones: Inhibition of 5‐lipoxygenase and stability in human blood and HepaRG cells.Pharmacology Research & Perspectives, 7(5). https://doi.org/10.1002/prp2.524
  • Roy, J., Saucier, D., O’Connell, C., & Morin, P. J. (2019). Extracellular vesicles and their diagnostic potential in amyotrophic lateral sclerosis.Clinica Chimica Acta, 497, 27–34. https://doi.org/10.1016/j.cca.2019.07.012
  • Saucier, D., Wajnberg, G., Roy, J., Beauregard, A. P., Chacko, S., Crapoulet, N., Fournier, S., Ghosh, A., Lewis, S. M., Marrero, A., O’Connell, C., Ouellette, R. J., & Morin, P. J. (2019). Identification of a circulating miRNA signature in extracellular vesicles collected from amyotrophic lateral sclerosis patients. Brain Research, 1708, 100–108. https://doi.org/10.1016/j.brainres.2018.12.016

 

  • Bathini, S., Raju, D., Badilescu, S., Kumar, A., Ouellette, R. J., Ghosh, A., & Packirisamy, M. (2018). Nano–Bio Interactions of Extracellular Vesicles with Gold Nanoislands for Early Cancer Diagnosis.Research, 2018, 1–10. https://doi.org/10.1155/2018/3917986
  • Gagnon, K., Lefort, N., Poirier, S., Barnett, D., & Surette, M. (2018). 5-lipoxygenase-dependent biosynthesis of novel 20:4 n-3 metabolites with anti-inflammatory activity.Prostaglandins, Leukotrienes and Essential Fatty Acids, 138, 38–44. https://doi.org/10.1016/j.plefa.2018.10.005
  • Harquail, J., LeBlanc, N., Landry, C., Crapoulet, N., & Robichaud, G. A. (2018). Pax-5 Inhibits NF-κB Activity in Breast Cancer Cells Through IKKε and miRNA-155 Effectors.Journal of Mammary Gland Biology and Neoplasia, 23(3), 177–187. https://doi.org/10.1007/s10911-018-9404-4
  • Leblanc, N., Harquail, J., Crapoulet, N., Ouellette, R. J., & Robichaud, G. A. (2018). Pax-5 Inhibits Breast Cancer Proliferation Through MiR-215 Up-regulation.Anticancer Research, 38(9), 5013–5026. https://doi.org/10.21873/anticanres.12820
  • Joy, A. P., Ayre, D. C., Chute, I. C., Beauregard, A. P., Wajnberg, G., Ghosh, A., Lewis, S. M., Ouellette, R. J., & Barnett, D. A. (2018). Proteome profiling of extracellular vesicles captured with the affinity peptide Vn96: comparison of Laemmli and TRIzol© protein-extraction methods.Journal of Extracellular Vesicles, 7(1), 1438727. https://doi.org/10.1080/20013078.2018.1438727
  • Razaghi, B., Steele, S. L., Prykhozhij, S. V., Stoyek, M. R., Hill, J. A., Cooper, M. D., McDonald, L., Lin, W., Daugaard, M., Crapoulet, N., Chacko, S., Lewis, S. M., Scott, I. C., Sorensen, P. H. B., & Berman, J. N. (2017b). hace1Influences zebrafish cardiac development via ROS-dependent mechanisms.Developmental Dynamics, 247(2), 289–303. https://doi.org/10.1002/dvdy.24600
  • Théry, C., Witwer, K. W., Aikawa, E., Alcaraz, M. J., Anderson, J. D., Andriantsitohaina, R., Antoniou, A., Arab, T., Archer, F., Atkin-Smith, G. K., Ayre, D. C., Bach, J. M., Bachurski, D., Baharvand, H., Balaj, L., Baldacchino, S., Bauer, N. N., Baxter, A. A., Bebawy, M., . . . Zuba-Surma, E. K. (2018). Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines.Journal of Extracellular Vesicles, 7(1), 1535750. https://doi.org/10.1080/20013078.2018.1535750
  • Ayre, D. C., Chute, I. C., Joy, A. P., Barnett, D. A., Hogan, A. M., Grüll, M. P., Peña-Castillo, L., Lang, A. S., Lewis, S. M., & Christian, S. L. (2017). CD24 induces changes to the surface receptors of B cell microvesicles with variable effects on their RNA and protein cargo. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-08094-8

  • Belkaid, A., Ouellette, R. J., & Surette, M. E. (2017). 17β-estradiol-induced ACSL4 protein expression promotes an invasive phenotype in estrogen receptor positive mammary carcinoma cells.Carcinogenesis, 38(4), 402–410. https://doi.org/10.1093/carcin/bgx020

  • Benzina, S., Beauregard, A. P., Guerrette, R., Jean, S., Faye, M. D., Laflamme, M., Maïcas, E., Crapoulet, N., Ouellette, R. J., & Robichaud, G. A. (2017). Pax-5 is a potent regulator of E-cadherin and breast cancer malignant processes. Oncotarget, 8(7), 12052–12066. https://doi.org/10.18632/oncotarget.14511

  • Bouhamdani, N., Joy, A., Barnett, D., Cormier, K., Léger, D., Chute, I. C., Lamarre, S., Ouellette, R., & Turcotte, S. (2017). Quantitative proteomics to study a small molecule targeting the loss of von Hippel-Lindau in renal cell carcinomas. International Journal of Cancer, 141(4), 778–790. https://doi.org/10.1002/ijc.30774

  • Griffiths, S., Cormier, M., Clayton, A., & Doucette, A. (2017). Differential Proteome Analysis of Extracellular Vesicles from Breast Cancer Cell Lines by Chaperone Affinity Enrichment. Proteomes, 5(4), 25. https://doi.org/10.3390/proteomes5040025

  • Morin, M. D., Frigault, J. J., Lyons, P. J., Crapoulet, N., Boquel, S., Storey, K. B., & Morin, P. J. (2017). Amplification and quantification of cold-associated microRNAs in the Colorado potato beetle (Leptinotarsa decemlineata) agricultural pest. Insect Molecular Biology, 26(5), 574–583. https://doi.org/10.1111/imb.12320

  • Morin, M.D., Lyons, P.J., Crapoulet, N., Boquel, S., & Morin, P. (2017). Identification of Differentially Expressed miRNAs in Colorado Potato Beetles (Leptinotarsa decemlineata (Say)) Exposed to Imidacloprid. International Journal of Molecular Sciences, 18(12), 2728. https://doi.org/10.3390/ijms18122728

  • Morin, M. D., Lang-Ouellette, D., Lyons, P. J., Crapoulet, N., & Morin Jr, P. (2017). Characterization of miRNAs modulated by torpor in the hibernating ground squirrel Ictidomys tridecemlineatus liver by next-generation sequencing.CryoLetters, 38(4). https://pubmed.ncbi.nlm.nih.gov/29734428/

  • Nguyen, N., Kumar, A., Chacko, S., Ouellette, R. J., & Ghosh, A. (2017). Human hyaluronic acid synthase-1 promotes malignant transformation via epithelial-to-mesenchymal transition, micronucleation and centrosome abnormalities.Cell Communication and Signaling, 15(1). https://doi.org/10.1186/s12964-017-0204-z

  • Razaghi, B., Steele, S. L., Prykhozhij, S. V., Stoyek, M. R., Hill, J. A., Cooper, M. D., McDonald, L., Lin, W., Daugaard, M., Crapoulet, N., Chacko, S., Lewis, S. M., Scott, I. C., Sorensen, P. H. B., & Berman, J. N. (2017). hace1Influences zebrafish cardiac development via ROS-dependent mechanisms. Developmental Dynamics247(2), 289–303. https://doi.org/10.1002/dvdy.24600

  • Salsman, J., Stathakis, A., Parker, E., Chung, D., Anthes, L. E., Koskowich, K. L., Lahsaee, S., Gaston, D., Kukurba, K. R., Smith, K. S., Chute, I. C., Léger, D., Frost, L. D., Montgomery, S. B., Lewis, S. M., Eskiw, C., & Dellaire, G. (2017). PML nuclear bodies contribute to the basal expression of the mTOR inhibitor DDIT4. Scientific Reports7(1). https://doi.org/10.1038/srep45038

  • Wall, M. L., & Lewis, S. M. (2017b). Methylarginines within the RGG-Motif Region of hnRNP A1 Affect Its IRES Trans-Acting Factor Activity and Are Required for hnRNP A1 Stress Granule Localization and Formation. Journal of Molecular Biology, 429(2), 295–307. https://doi.org/10.1016/j.jmb.2016.12.011
  • Belkaid, A., Čuperlović-Culf, M., Touaibia, M., Ouellette, R., & Surette, M. (2016). Metabolic Effect of Estrogen Receptor Agonists on Breast Cancer Cells in the Presence or Absence of Carbonic Anhydrase Inhibitors. Metabolites, 6(2), 16. https://doi.org/10.3390/metabo6020016

  • Benzina, S., Harquail, J., Guerrette, R., O’Brien, P., Jean, S., Crapoulet, N., & Robichaud, G. A. (2016). Breast Cancer Malignant Processes are Regulated by Pax-5 Through the Disruption of FAK Signaling Pathways. Journal of Cancer, 7(14), 2035–2044. https://doi.org/10.7150/jca.15200

  • Culf, A. S., Yin, H., Monro, S., Ghosh, A., Barnett, D. A., Ouellette, R. J., Čuperlović-Culf, M., & McFarland, S. A. (2016). A spectroscopic study of substituted anthranilic acids as sensitive environmental probes for detecting cancer cells. Bioorganic & Medicinal Chemistry, 24(5), 929–937. https://doi.org/10.1016/j.bmc.2015.12.044

  • Cuperlovic-Culf, M., Cormier, K., Touaibia, M., Reyjal, J., Robichaud, S., Belbraouet, M., & Turcotte, S. (2016). 1H NMR metabolomics analysis of renal cell carcinoma cells: Effect of VHL inactivation on metabolism. International Journal of Cancer, 138(10), 2439–2449. https://doi.org/10.1002/ijc.29947

  • Lyons, P. J., Govaere, L., Crapoulet, N., Storey, K. B., & Morin, P. J. (2016). Characterization of cold-associated microRNAs in the freeze-tolerant gall fly Eurosta solidaginis using high-throughput sequencing. Comparative Biochemistry and Physiology Part D: Genomics and Proteomics, 20, 95–100. https://doi.org/10.1016/j.cbd.2016.08.007

  • Morash, A. J., Mackellar, S. R. C., Tunnah, L., Barnett, D. A., Stehfest, K. M., Semmens, J. M., & Currie, S. (2016). Pass the salt: physiological consequences of ecologically relevant hyposmotic exposure in juvenile gummy sharks (Mustelus antarcticus) and school sharks (Galeorhinus galeus). Conservation Physiology, 4(1), cow036. https://doi.org/10.1093/conphys/cow03

  • Robichaud, P. P., Poirier, S. J., Boudreau, L. H., Doiron, J. A., Barnett, D. A., Boilard, E., & Surette, M. E. (2016). On the cellular metabolism of the click chemistry probe 19-alkyne arachidonic acid. Journal of Lipid Research, 57(10), 1821–1830. https://doi.org/10.1194/jlr.m067637
  • Tunnah, L., Mackellar, S. R. C., Barnett, D. A., Maccormack, T. J., Stehfest, K. M., Morash, A. J., Semmens, J. M., & Currie, S. (2016). Physiological responses to hypersalinity correspond to nursery ground usage in two inshore shark species (Mustelus antarcticus & Galeorhinus galeus). Journal of Experimental Biology. Published. https://doi.org/10.1242/jeb.139964
  • Beauregard, A. P., Harquail, J., Lassalle-Claux, G., Belbraouet, M., Jean-Francois, J., Touaibia, M., & Robichaud, G. (2015). CAPE Analogs Induce Growth Arrest and Apoptosis in Breast Cancer Cells. Molecules, 20(7), 12576–12589. https://doi.org/10.3390/molecules200712576
  • Belkaid, A., Duguay, S. R., Ouellette, R. J., & Surette, M. E. (2015). 17β-estradiol induces stearoyl-CoA desaturase-1 expression in estrogen receptor-positive breast cancer cells. BMC Cancer, 15(1). https://doi.org/10.1186/s12885-015-1452-1
  • Christiaens, A. B., Deprez, P. M. L., Amyere, M., Mendola, A., Bernard, P., Gillerot, Y., Clapuyt, P., Godfraind, C., Lengelé, B. G., Vikkula, M., & Nyssen-Behets, C. (2015). Isolated bilateral transverse agenesis of the distal segments of the lower limbs at the level of the knee joint in a human fetus. American Journal of Medical Genetics Part A, 170(2), 523–530. https://doi.org/10.1002/ajmg.a.37462
  • Culf, A. S., Čuperlović-Culf, M., Ouellette, R. J., & Decken, A. (2015). Metal-Free, Acid-Catalyzed ortho-Directed Synthesis of Anthranilic Acid Derivatives Using Carbodiimides. Organic Letters, 17(11), 2744–2747. https://doi.org/10.1021/acs.orglett.5b01160
  • Desnoyers, G., Frost, L. D., Courteau, L., Wall, M. L., & Lewis, S. M. (2015). Decreased eIF3e Expression Can Mediate Epithelial-to-Mesenchymal Transition through Activation of the TGFβ Signaling Pathway. Molecular Cancer Research, 13(10), 1421–1430. https://doi.org/10.1158/1541-7786.mcr-14-0645
  • Deveau, A. P., Forrester, A. M., Coombs, A. J., Wagner, G. S., Grabher, C., Chute, I. C., Léger, D., Mingay, M., Alexe, G., Rajan, V., Liwski, R., Hirst, M., Stegmaier, K., Lewis, S. M., Look, A. T., & Berman, J. N. (2015). Epigenetic therapy restores normal hematopoiesis in a zebrafish model of NUP98–HOXA9-induced myeloid disease. Leukemia, 29(10), 2086–2097. https://doi.org/10.1038/leu.2015.126
  • Li, H., Jean, S., Webster, D., Robichaud, G. A., Calhoun, L. A., Johnson, J. A., & Gray, C. A. (2015). Dibenz[b,f]oxepin and Antimycobacterial Chalcone Constituents ofEmpetrum nigrum. Journal of Natural Products, 78(11), 2837–2840. https://doi.org/10.1021/acs.jnatprod.5b00627
  • Lyons, P. J., Crapoulet, N., Storey, K. B., & Morin, P. J. (2015). Identification and profiling of miRNAs in the freeze-avoiding gall moth Epiblema scudderiana via next-generation sequencing. Molecular and Cellular Biochemistry, 410(1–2), 155–163. https://doi.org/10.1007/s11010-015-2547-3
  • MacLellan, R. J., Tunnah, L., Barnett, D., Wright, P. A., MacCormack, T., & Currie, S. (2015). Chaperone roles for TMAO and HSP70 during hyposmotic stress in the spiny dogfish shark (Squalus acanthias). Journal of Comparative Physiology B, 185(7), 729–740. https://doi.org/10.1007/s00360-015-0916-6
  • Picot, N., Guerrette, R., Beauregard, A. P., Jean, S., Michaud, P., Harquail, J., Benzina, S., & Robichaud, G. A. (2015). Mammaglobin 1 promotes breast cancer malignancy and confers sensitivity to anticancer drugs. Molecular Carcinogenesis, 55(7), 1150–1162. https://doi.org/10.1002/mc.22358
  • Cormier, K., Harquail, J., Ouellette, R., Tessier, P., Guerrette, R., & Robichaud, G. (2014). Intracellular Expression of Inflammatory Proteins S100A8 and S100A9 Leads to Epithelial-mesenchymal Transition and Attenuated Aggressivity of Breast Cancer Cells. Anti-Cancer Agents in Medicinal Chemistry, 14(1), 35–45. https://doi.org/10.2174/18715206113136660333
  • Culf, A. S., Čuperlović-Culf, M., Léger, D. A., & Decken, A. (2014). Small Head-to-Tail Macrocyclic α-Peptoids. Organic Letters, 16(10), 2780–2783. https://doi.org/10.1021/ol501102b
  • Cuperlovic-Culf, M., Touaibia, M., St-Coeur, P. D., Poitras, J., Morin, P., & Culf, A. (2014). Metabolic Effects of Known and Novel HDAC and SIRT Inhibitors in Glioblastomas Independently or Combined with Temozolomide. Metabolites, 4(3), 807–830. https://doi.org/10.3390/metabo4030807
  • Ghosh, A., Davey, M., Chute, I. C., Griffiths, S. G., Lewis, S., Chacko, S., Barnett, D., Crapoulet, N., Fournier, S., Joy, A., Caissie, M. C., Ferguson, A. D., Daigle, M., Meli, M. V., Lewis, S. M., & Ouellette, R. J. (2014). Rapid Isolation of Extracellular Vesicles from Cell Culture and Biological Fluids Using a Synthetic Peptide with Specific Affinity for Heat Shock Proteins. PLoS ONE, 9(10), e110443. https://doi.org/10.1371/journal.pone.0110443

  • Lefort, N., Brown, A., Lloyd, V., Ouellette, R., Touaibia, M., Culf, A. S., & Cuperlovic-Culf, M. (2014). 1H NMR metabolomics analysis of the effect of dichloroacetate and allopurinol on breast cancers. Journal of Pharmaceutical and Biomedical Analysis, 93, 77–85. https://doi.org/10.1016/j.jpba.2013.08.017

  • Scarborough, R. J., Lévesque, M. V., Boudrias-Dalle, E., Chute, I. C., Daniels, S. M., Ouellette, R. J., Perreault, J. P., & Gatignol, A. (2014). A Conserved Target Site in HIV-1 Gag RNA is Accessible to Inhibition by Both an HDV Ribozyme and a Short Hairpin RNA. Molecular Therapy - Nucleic Acids, 3, e178. https://doi.org/10.1038/mtna.2014.31
  • Whidden, C. E., DeZeeuw, K. G., Zorz, J. K., Joy, A. P., Barnett, D. A., Johnson, M. S., Zhaxybayeva, O., & Cockshutt, A. M. (2014). Quantitative and Functional Characterization of the Hyper-Conserved Protein of Prochlorococcus and Marine Synechococcus. PLoS ONE, 9(10), e109327. https://doi.org/10.1371/journal.pone.0109327
  • Epple, L. M., Griffiths, S. G., Dechkovskaia, A. M., Dusto, N. L., White, J., Ouellette, R. J., Anchordoquy, T. J., Bemis, L. T., & Graner, M. W. (2012). Medulloblastoma Exosome Proteomics Yield Functional Roles for Extracellular Vesicles. PLoS ONE, 7(7), e42064. https://doi.org/10.1371/journal.pone.0042064
  • Gillis, L. D., & Lewis, S. M. (2012). Decreased eIF3e/Int6 expression causes epithelial-to-mesenchymal transition in breast epithelial cells. Oncogene, 32(31), 3598–3605. https://doi.org/10.1038/onc.2012.371
  • Harquail, J., Benzina, S., & Robichaud, G. A. (2012). MicroRNAs and breast cancer malignancy: An overview of miRNA-regulated cancer processes leading to metastasis. Cancer Biomarkers, 11(6), 269–280. https://doi.org/10.3233/cbm-120291
  • Massé, P. G., Boudreau, J., Tranchant, C. C., Ouellette, R., & Ericson, K. L. (2012). Type 1 diabetes impairs vitamin B6 metabolism at an early stage of women’s adulthood. Applied Physiology, Nutrition, and Metabolism, 37(1), 167–175. https://doi.org/10.1139/h11-146
  • Tao, T., Robichaud, A., Mercier, J., & Ouellette, R. (2012). Influence of group embryo culture strategies on the blastocyst development and pregnancy outcome. Journal of Assisted Reproduction and Genetics, 30(1), 63–68. https://doi.org/10.1007/s10815-012-9892-x
  • Barnett, D. A., & Ouellette, R. J. (2011). Elimination of the helium requirement in high-field asymmetric waveform ion mobility spectrometry (FAIMS): beneficial effects of decreasing the analyzer gap width on peptide analysis. Rapid Communications in Mass Spectrometry, 25(14), 1959–1971. https://doi.org/10.1002/rcm.5078
  • Crapoulet, N., O’Brien, P., J. Ouellette, R., & A. Robichaud, G. (2011). Coordinated Expression of Pax-5 and FAK1 in Metastasis. Anti-Cancer Agents in Medicinal Chemistry, 11(7), 643–649. https://doi.org/10.2174/187152011796817637
  • Doiron, J., Soultan, A. H., Richard, R., Touré, M. M., Picot, N., Richard, R., Čuperlović-Culf, M., Robichaud, G. A., & Touaibia, M. (2011). Synthesis and structure–activity relationship of 1- and 2-substituted-1,2,3-triazole letrozole-based analogues as aromatase inhibitors. European Journal of Medicinal Chemistry, 46(9), 4010–4024. https://doi.org/10.1016/j.ejmech.2011.05.074
  • Narayansingh, R., & Ouellette, R. J. (2011). Paired box gene 5 may modulate Proviral Integration of Moloney virus2gene and protein expression in mature B-cells. Leukemia & Lymphoma, 52(5), 887–895. https://doi.org/10.3109/10428194.2011.553001
  • O’Brien, P., Morin, P., Ouellette, R. J., & Robichaud, G. A. (2011). The Pax-5 Gene: A Pluripotent Regulator of B-cell Differentiation and Cancer Disease: Figure 1. Cancer Research, 71(24), 7345–7350. https://doi.org/10.1158/0008-5472.can-11-1874
  • Booman, M., Borza, T., Feng, C. Y., Hori, T. S., Higgins, B., Culf, A., Léger, D., Chute, I. C., Belkaid, A., Rise, M., Gamperl, A. K., Hubert, S., Kimball, J., Ouellette, R. J., Johnson, S. C., Bowman, S., & Rise, M. L. (2010). Development and Experimental Validation of a 20K Atlantic Cod (Gadus morhua) Oligonucleotide Microarray Based on a Collection of over 150,000 ESTs. Marine Biotechnology, 13(4), 733–750. https://doi.org/10.1007/s10126-010-9335-6
  • Cuperlovic-Culf, M., Belacel, N., Davey, M., & Ouellette, R. J. (2010). Multi-gene biomarker panel for reference free prostate cancer diagnosis: determination and independent validation. Biomarkers, 15(8), 693–706. https://doi.org/10.3109/1354750x.2010.511268
  • Cuperlovic-Culf, M., Belacel, N., Davey, M., & Ouellette, R. J. (2010). Multi-gene biomarker panel for reference free prostate cancer diagnosis: determination and independent validation. Biomarkers, 15(8), 693–706. https://doi.org/10.3109/1354750x.2010.511268
  • Arseneau, J. R., Laflamme, M., Lewis, S. M., Maïcas, E., & Ouellette, R. J. (2009). Multiple isoforms ofPAX5are expressed in both lymphomas and normal B-cells. British Journal of Haematology, 147(3), 328–338. https://doi.org/10.1111/j.1365-2141.2009.07859.x
  • Čuperlović-Culf, M., Belacel, N., Culf, A. S., Chute, I. C., Ouellette, R. J., Burton, I. W., Karakach, T. K., & Walter, J. A. (2009). NMR metabolic analysis of samples using fuzzy K-means clustering. Magnetic Resonance in Chemistry, 47(S1), S96–S104. https://doi.org/10.1002/mrc.2502
  • Culf, A. S., Čuperlović-Culf, M., Laflamme, M., Tardiff, B. J., & Ouellette, R. J. (2008). Fast Deprotection of Synthetic Oligodeoxyribonucleotides Using Standard Reagents under Microwave Irradiation. Oligonucleotides, 18(1), 81–92. https://doi.org/10.1089/oli.2007.0072
  • Culf, A. S., Čuperlović-Culf, M., & Ouellette, R. J. (2008). Chemical exchange in novel spirobicyclic zwitterionic Janovsky complexes using dynamic 1H NMR spectroscopy. Magnetic Resonance in Chemistry, 47(2), 158–164. https://doi.org/10.1002/mrc.2368
  • Robichaud, G. A., Perreault, J. P., & Ouellette, R. J. (2008). Development of an isoform-specific gene suppression system: the study of the human Pax-5B transcriptional element. Nucleic Acids Research, 36(14), 4609–4620. https://doi.org/10.1093/nar/gkn432
  • Laflamme, M., & Robichaud, G. A. (2007). Gene Suppression Technologies in High-Throughput Analysis: Front- and Back-side Applications.OMICS: A Journal of Integrative Biology, 11(2), 129–142. https://doi.org/10.1089/omi.2007.4321

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